Energy-linked reactions of biotin-deficient rat liver mitoghondria

Autor:	K. Dakshinamurti, C. Bhuvaneswaran
Rok vydání:	1974
Předmět:	High energy chemistry.chemical_compound Rat liver mitochondria Biotin chemistry Biochemistry Rat liver NAD+ kinase Mitochondrion Biology
Zdroj:	International Journal of Biochemistry. 5:819-822
ISSN:	0020-711X
DOI:	10.1016/0020-711x(74)90116-5
Popis:	1. 1. Biotin-deficient rat liver mitochondria showed decreased Ca 2+ : O ratio as compared to normal rat liver mitochondria when NAD + -linked substrates were oxidized, but not when succinate was oxidized, indicating a damage at the energy conservation site I. 2. 2. Succinate-linked reduction of acetoacetate using aerobically-generated high energy intermediate was also decreased in the biotin-deficient rat liver mitochondria. 3. 3. Administration of 200 μg. of biotin to deficient animals restored the succinate-linked reduction of acetoacetate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1c9863466ebe440e914ba42513234338 https://doi.org/10.1016/0020-711x(74)90116-5 Zobrazit plný text záznamu