Influence of pressure on the low-frequency vibrational modes of lysozyme and water: A complementary inelastic neutron scattering and molecular dynamics simulation study
| Autor: | Marie-Claire Bellissent-Funel, Alain Hédoux, Burkhard Annighöfer, Adrien Lerbret |
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| Rok vydání: | 2012 |
| Předmět: |
Aqueous solution
010304 chemical physics Chemistry Protein dynamics Low frequency 010402 general chemistry 01 natural sciences Biochemistry Inelastic neutron scattering 0104 chemical sciences Crystallography chemistry.chemical_compound Molecular dynamics Structural Biology Chemical physics Molecular vibration 0103 physical sciences Compressibility Lysozyme Molecular Biology |
| Zdroj: | Proteins: Structure, Function, and Bioinformatics. 81:326-340 |
| ISSN: | 0887-3585 |
| DOI: | 10.1002/prot.24189 |
| Popis: | We performed complementary inelastic neutron scattering (INS) experiments and molecular dynamics (MD) simulations to study the influence of pressure on the low-frequency vibrational modes of lysozyme in aqueous solution in the 1 atm–6 kbar range. Increasing pressure induces a high-frequency shift of the low-frequency part ( |
| Databáze: | OpenAIRE |
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