Synthesis and Structure of an Enantiomerically Pure C2 Symmetric Ferrocenyl Carbene
Autor: | Antonio Togni, Diego Broggini |
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Rok vydání: | 2002 |
Předmět: | |
Zdroj: | Helvetica Chimica Acta. 85:2518-2522 |
ISSN: | 1522-2675 0018-019X |
DOI: | 10.1002/1522-2675(200208)85:8<2518::aid-hlca2518>3.0.co;2-n |
Popis: | The straightforward, high-yield synthesis and X-ray structural analysis of the air-stable planar-chiral bis(ferrocenyl)carbene 1,3-bis-{(1R)-1-[(1R)-1-(trimethylsilyl)ferrocen-2-yl]ethyl}imidazol-2-ylidene (5) is reported. Compound 5 is obtained in four steps from the amine [(1R)-1-(dimethylamino)ethyl]ferrocene (1) upon diastereoselective silylation, methylation, nucleophilic substitution by imidazole, and deprotonation. The X-ray crystal structure of the free carbene shows the typical conformational features of the 1,2-disubstituted ferrocenyl units, as found in other ferrocenyl ligands derived from 1. |
Databáze: | OpenAIRE |
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