| Autor: |
Bruce A. Littlefield, O. L. Kon, J. Hora, Patricia A. Boyd-leinen, Kay Rasmussen, Amy Goldberger, G. Martin-Dani, Barbara Gosse, Thomas C. Spelsberg |
| Rok vydání: |
1984 |
| Předmět: |
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| Zdroj: |
IUPHAR 9th International Congress of Pharmacology London 1984 ISBN: 9780333371367 |
| DOI: |
10.1007/978-1-349-17615-1_14 |
| Popis: |
Steroids alter the metabolism and functions of their target tissues due to the presence of specific binding proteins termed ‘receptors’. The binding of these receptors by steroids results in ‘activation’, a process whereby the steroid-receptor complex is endowed with the capacity to bind to specific nuclear sites, termed nuclear ‘acceptor’ sites. The results of this nuclear binding are steroid-induced alterations in the transcription of many genes, as well as changes in the abundances of many gene products (O’Malley & Means, 1974; Thrall et al., 1978). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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