A NewGγ Chain Variant: Hb F-Bron [γ20(B2)Val→Ala]

Ala] on the first exon of the G(gamma)-globin gene is described. The variant was characterized by DNA sequencing and mass spectrometry (MS). Hematological abnormalities included hypochromia and microcytosis and were probably caused by an interaction with an alpha-thalassemia (thal) (3.7 kb) deletion in the heterozygous state. -->

ISSN:	1532-432X 0363-0269
DOI:	10.1080/03630260500312725
Přístupová URL adresa:	https://explore.openaire.eu/search/publication?articleId=doi_________::1c686b228979d8a24f5fc1a502eee353 https://doi.org/10.1080/03630260500312725
Přírůstkové číslo:	edsair.doi...........1c686b228979d8a24f5fc1a502eee353
Autor:	Michel Becchi, Philippe Lacan, Nicole Couprie, Martine Aubry, Nelly Burnichon, Isabelle Zanella-Cléon, Alain Francina
Rok vydání:	2005
Předmět:	Chemistry Microcytosis Biochemistry (medical) Clinical Biochemistry Hematology Alpha-thalassemia medicine.disease Molecular biology DNA sequencing Exon Fetal hemoglobin Hypochromia medicine Globin Hemoglobin Genetics (clinical)
Zdroj:	Hemoglobin. 29:301-305
ISSN:	1532-432X 0363-0269
DOI:	10.1080/03630260500312725
Popis:	A new G(gamma) hemoglobin (Hb) variant, Hb F-Bron [gamma20(B2)Val-->Ala] on the first exon of the G(gamma)-globin gene is described. The variant was characterized by DNA sequencing and mass spectrometry (MS). Hematological abnormalities included hypochromia and microcytosis and were probably caused by an interaction with an alpha-thalassemia (thal) (3.7 kb) deletion in the heterozygous state.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1c686b228979d8a24f5fc1a502eee353 https://doi.org/10.1080/03630260500312725 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.