Inhibition of Proliferation and Induction of Apoptosis of HT-29 Colorectal Adenocarcinoma Cells in Vitro by Anthocyanins from Lonicera Edulis

Autor:	Yi Hong Bao, Wen Xing Li, Zhenyu Wang
Rok vydání:	2011
Předmět:	Antioxidant medicine.diagnostic_test Chemistry medicine.medical_treatment General Engineering food and beverages Molecular biology In vitro Flow cytometry chemistry.chemical_compound HT29 Cells In vivo Apoptosis Anthocyanin medicine Growth inhibition
Zdroj:	Advanced Materials Research. :2945-2948
ISSN:	1662-8985
Popis:	Anthocyanins was known for their antioxidant and pharmacological properties used by humans for therapeutic purposes. Here, we study the inhibitory effects of anthocyanins fromLonicera edulison the proliferation of HT-29 colorectal adenocarcinoma cells and its possible mechanism in vivo by MTT. The different percentages of apoptotic cells present in flow cytometry analysis. The effect on HT29 cells was enhanced with increasing amount of anthocyanins. Typical morphological features of apoptosis were observed by transmission electron microscope. The mechanism of anthocyanins from Lonicera edulis on HT29 cell growth inhibition may be related to the induction of apoptosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1c087dafbb000f3e1c742eb522122752 https://doi.org/10.4028/www.scientific.net/amr.233-235.2945 Zobrazit plný text záznamu