The First Biosynthetic Studies of the Azinomycins: Acetate Incorporation into Azinomycin B

Autor:	Christophe Corre, Philip A. S. Lowden
Rok vydání:	2004
Předmět:	chemistry.chemical_compound education.field_of_study Polyketide Natural product chemistry Stereochemistry General Medicine Aziridine Threonine education Azinomycin B Enol
Zdroj:	ChemInform. 35
ISSN:	1522-2667 0931-7597
Popis:	13 C-Labelled acetate efficiently labels the antitumour natural product azinomycin B, revealing a polyketide origin for the naphthoate fragment, that threonine is the probable precursor of the enol fragment, and that α-ketoglutarate is a probable precursor of the aziridine fragment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1be5780d84972a642bd9ffb077d49b64 https://doi.org/10.1002/chin.200435224 Zobrazit plný text záznamu Plný text