Nanoencapsulation of Lutein with Hydroxypropylmethyl Cellulose Phthalate by Supercritical Antisolvent
| Autor: | Yaping Zhao, Lin He, Heyang Jin, Fei Xia, Cuilan Jiang |
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| Rok vydání: | 2009 |
| Předmět: |
endocrine system
Lutein Environmental Engineering Chromatography Scanning electron microscope General Chemical Engineering Phthalate food and beverages General Chemistry Biochemistry eye diseases Nanocapsules Supercritical fluid chemistry.chemical_compound chemistry Hydroxypropylmethyl cellulose Particle-size distribution sense organs Particle size |
| Zdroj: | Chinese Journal of Chemical Engineering. 17:672-677 |
| ISSN: | 1004-9541 |
| DOI: | 10.1016/s1004-9541(08)60262-1 |
| Popis: | Lutein was nano-encapsuled with hydroxypropylmethyl cellulose phthalate (HPMCP) to maintain its bioactivity and to avoid thermal/light degradation. Supercritical antisolvent precipitation was applied to prepare lutein/HPMCP nano-capsule. The effects of several operating parameters on the yield, lutein loading, encapsulation efficiency, particle size and particle size distribution of the nanocapsule were investigated. The mean diameter of nanocapsules ranged from 163 nm to 219 nm under appropriate experimental conditions. The result of scanning electron microscope showed that the nanocapsules were nearly spherical. The highest yield reached 95.35% when the initial concentration of lutein was saturated. The highest lutein loading of 15.80% and encapsulation efficiency of 88.41% were obtained under the conditions of 11 MPa, 40°C and CHPMCP:Clutein = 5:l. The results may promote the application of lutein in food industry. |
| Databáze: | OpenAIRE |
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