Morphine uptake, disposition, and analgesic efficacy in the common goldfish (Carassius auratus)

Autor:	Michael P. Wilkie, E. D. Stevens, N. C. Newby
Rok vydání:	2009
Předmět:	Analgesic Biology Pharmacology Common goldfish Route of administration Subcutaneous injection Acetic acid chemistry.chemical_compound Pharmacokinetics chemistry Noxious stimulus Morphine medicine Animal Science and Zoology Ecology Evolution Behavior and Systematics medicine.drug
Zdroj:	Canadian Journal of Zoology. 87:388-399
ISSN:	1480-3283 0008-4301
DOI:	10.1139/z09-023
Popis:	The purposes of the present study were to examine the rate of morphine uptake in goldfish ( Carassius auratus (L., 1758)) when administered via the water, to calculate the pharmacokinetics of morphine when administered intraperitoneally, and to determine whether morphine could act as an analgesic. When administered via the water, morphine uptake was very slow, and the concentration accumulated in the plasma was
Databáze:	OpenAIRE
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