The relationship between the level of neuroactive steroids in the brain, behavior, and anxiety in male rats with different hormonal status
Autor: | V. A. Sashkov |
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Rok vydání: | 2009 |
Předmět: |
medicine.medical_specialty
Neuroactive steroid Hippocampus Biochemistry Amygdala Cellular and Molecular Neuroscience chemistry.chemical_compound medicine.anatomical_structure Endocrinology nervous system chemistry Corticosterone Hypothalamus Internal medicine medicine Anxiety medicine.symptom Psychology Molecular Biology Testosterone Hormone |
Zdroj: | Neurochemical Journal. 3:98-106 |
ISSN: | 1819-7132 1819-7124 |
DOI: | 10.1134/s1819712409020044 |
Popis: | We investigated the levels of neuroactive steroids, behavior, and anxiety in the brains of male rats with different hormonal status. We revealed a correlation between motor and exploratory activities, emotionality, and anxiety and the concentrations of corticosterone, testosterone, and estradiol in the hypothalamus, hippocampus, amygdala, cingulated gyrus, and frontal cortex in intact male rats, as well as in animals with experimentally high or low levels of sex steroids. The correlation analysis confirmed the selective involvement of different brain structures and neuroactive steroids in brain functioning and behavioral adaptation. |
Databáze: | OpenAIRE |
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