| Popis: |
The scientific literature during the last ten years has seen an increase in the number of reports claiming links for genetic polymorphisms with a variety of medical diseases, particularly chronic immune and inflammatory conditions. Recently, periodontal research has contributed to this growth area. These new research affects the understanding of the genome which, in turn, has permitted the functional relationships of gene products with each other and with environmental agents to be understood. As a result of this knowledge explosion, it is evident that there is a genetic basis for most diseases, including periodontitis. This realization has fostered the idea that if we can understand the genetic basis of diseases, genetic tests to assess disease risk and to develop etiology-based treatments will soon be reality. Consequently, it is important to identify the allelic variants of genes that can be used to assess disease risk for periodontal diseases. |
