Acquired hippocampal damage after temporal lobe seizures in 2 infants

Autor:	Kathleen Meagher Villemure, Virgini Chaves Vischer, Jean-Guy Villemure, Philippe Maeder, Eliane Roulet Perez, Thierry Deonna
Rok vydání:	2000
Předmět:	Hippocampal sclerosis medicine.diagnostic_test Hippocampus Magnetic resonance imaging Status epilepticus Hippocampal formation medicine.disease Temporal lobe Central nervous system disease Dysgenesis Neurology medicine Neurology (clinical) medicine.symptom Psychology Neuroscience
Zdroj:	Annals of Neurology. 48:384-387
ISSN:	0364-5134
DOI:	10.1002/1531-8249(200009)48:3<384::aid-ana15>3.0.co;2-n
Popis:	Two infants developed unilateral hippocampal swelling on magnetic resonance imaging after prolonged seizures of temporal origin. Subsequent images suggested hippocampal sclerosis. The first child had febrile status epilepticus with exanthem subitum and developed refractory complex partial seizures. Histological findings after temporal lobectomy confirmed hippocampal sclerosis but also revealed sequelae of a focal encephalitis and microdysgenesis of the hippocampus. The second child had signs of brain dysgenesis, but acquired hippocampal damage affecting each side successively was documented by serial magnetic resonance imaging. These cases illustrate that different clinical conditions combining preexisting and acquired pathological characteristics can lead to hippocampal sclerosis. Ann Neurol 2000;48:384–387
Databáze:	OpenAIRE
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