Utilizing the 2017–2018 seasonal influenza vaccine as a treatment for cancer

Autor:	Jenna H. Newman, Charles Brent Chesson, Salvatore Aspromonte, Praveen K. Bommareddy, Russell Pepe, Saeed Tarabichi, Shengguo Li, Sachin Jhawar, Nora L. Herzog, Mones Aboelatta, Eshan Kaul, Ricardo Estupinian, Michael P. Kane, Ann Silk, Andrew Zloza
Rok vydání:	2018
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 200:178.44-178.44
ISSN:	1550-6606 0022-1767
DOI:	10.4049/jimmunol.200.supp.178.44
Popis:	In recent years, immunotherapy has yielded increased survival for cancer patients; however, a significant percentage of patient tumors remain refractory to immunotherapy. This is due in part to the absence of an inflamed tumor microenvironment. In our effort to utilize anti-pathogen vaccination to recruit immune cells to un-infiltrated (cold) tumors, we observed that intratumoral injection of influenza A/PR8/H1N1 lysate (but not live virus) reduced B16-F10 melanoma growth (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1b8d8cbf3234705517b279fa42201a8b https://doi.org/10.4049/jimmunol.200.supp.178.44 Zobrazit plný text záznamu