Popis: |
In this work the study of the effect of millimeter range electromagnetic waves (MM EMW) on methyl violet interaction with human serum albumin (HSA) has been carried out, using the UV-denaturation, fluorescence spectroscopy and CD spectroscopy methods. It was revealed that MM EMW irradiation leads to weakening of the stability of HSA and decreasing of interaction force between HSA and methyl violet (MV). It was also shown that MM EMW irradiation by water non-resonant frequency, affecting immediately the structure of HSA, changes its secondary structure, while the irradiation by water-resonant frequency does not invoke structural changes, but weakens the stability more. The last insistence results from the water cluster reconstruction, due to which the structured water affects the conformation of HSA. |