Primer reporte de Escherichia coli diarreogénica en población pediátrica ambulatoria con diarrea atendida en la ciudad de La Plata, Argentina
| Autor: | Nora Beatriz Molina, Sebastián Oderiz, Juan Ángel Basualdo, Cecilia Vescina, Alejandra Córdoba, Mónica Sparo |
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| Rok vydání: | 2022 |
| Předmět: |
Microbiology (medical)
0303 health sciences education.field_of_study biology 030306 microbiology Population Shiga toxin General Medicine medicine.disease_cause Microbiology 03 medical and health sciences Diarrhea Enterotoxigenic Escherichia coli Enteroaggregative Escherichia coli medicine biology.protein bacteria Enteropathogenic Escherichia coli medicine.symptom education Escherichia coli Enteroinvasive Escherichia coli |
| Zdroj: | Revista Argentina de Microbiología. 54:15-21 |
| ISSN: | 0325-7541 |
| Popis: | Diarrheagenic Escherichia coli is a heterogeneous group of strains that presents various virulence factors and causes different diarrheal syndromes. The most studied pathotypes are enteropathogenic Escherichia coli (EPEC), enterotoxigenic Escherichia coli (ETEC), enteroaggregative Escherichia coli (EAEC), enteroinvasive Escherichia coli (EIEC) and Shiga toxin-producing Escherichia coli (STEC). The objective was to estimate the frequency of infection of diarrheagenic E. coli pathotypes in children with diarrhea, attended at the Sor Maria Ludovica Hospital in La Plata, Argentina, during the period May-October 2017. E. coli pathotypes were detected by molecular amplification of eight characteristic virulence genes. The feces of 211 children (76% under 5 years) were studied. Infection with diarrheagenic E. coli was detected in 12.3% of the samples. The pathotypes were EAEC (10.43%), ETEC (1.42%, all of them positive for thermolabile toxin), EPEC (0.95%) and STEC (0.47%, positive for Shiga toxin 2). The EAEC pathotype was prevalent in children of all age groups, while ETEC, EPEC and STEC were only observed in children under 5 years of age. This study constitutes the first report of diarrheagenic Escherichia coli detection in an outpatient pediatric population with diarrhea from La Plata, using molecular amplification techniques. Broader future studies, including the characterization of the isolates with the largest number of genes, asymptomatic controls, different times of the year and population from different geographic areas will be necessary to clarify the relevance of diarrheagenic E. coli infection in children from Argentina. |
| Databáze: | OpenAIRE |
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