Total syntheses of naturally occurring spermidine alkaloids: (+)-(2S)-dihydromyricoidine and (+)-(2S)-myricoidine

Autor:	Ursula A. Häusermann, Manfred Hesse
Rok vydání:	1998
Předmět:	Spermidine chemistry.chemical_compound chemistry Stereochemistry Organic Chemistry Drug Discovery Absolute configuration Organic chemistry Biochemistry
Zdroj:	Tetrahedron Letters. 39:257-260
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(97)10568-8
Popis:	The spermidine alkaloids (+)-(2S)-dihydromyricoidine (5) and (+)-(2S)-myricoidine (4) were synthesized under asymmetric conditions. The synthetic compounds 4 and 5 were found to have positive [α] d 21 values in both cases, which agrees with those of the natural alkaloids. Therefore the absolute configuration of the natural products are (2S)-configurated and not (2R)- as reported in the literature.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1b332eae86686ce10625955b538e43bd https://doi.org/10.1016/s0040-4039(97)10568-8 Zobrazit plný text záznamu Full Text from ScienceDirect