Synthesis, characterization and hemolysis studies of Zn(1−x)CaxFe2O4 ferrites synthesized by sol-gel for hyperthermia treatment applications

Autor: J.M. Almanza-Robles, Laura Elena De-León-Prado, Rosario Argentina Jasso-Terán, J.C. Escobedo-Bocardo, Pamela Yajaira Reyes-Rodríguez, Héctor Javier Sánchez-Fuentes, Dora A. Cortés-Hernández
Rok vydání: 2017
Předmět:
Zdroj: Journal of Magnetism and Magnetic Materials. 427:241-244
ISSN: 0304-8853
Popis: The synthesis of Zn (1−x) Ca x Fe 2 O 4 nanoparticles, x=0, 0.25, 0.50, 0.75 and 1.0, was performed by sol-gel method followed by a heat treatment at 400 °C for 30 min. These ferrites showed nanometric sizes and nearly superparamagnetic behavior. The Zn 0.50 Ca 0.50 Fe 2 O 4 and CaFe 2 O 4 ferrites presented a size within the range of 12–14 nm and appropriate heating ability for hyperthermia applications. Hemolysis testing demonstrated that Zn 0.50 Ca 0.50 Fe 2 O 4 ferrite was not cytotoxic when using 10 mg of ferrite/mL of solution. According to the results obtained, Zn 0.50 Ca 0.50 Fe 2 O 4 is a potential material for cancer treatment by magnetic hyperthermia therapy.
Databáze: OpenAIRE