Modification of optically active ferrocenylphosphine ligands for palladium-catalyzed asymmetric allylic alkylation
| Autor: | Tamio Hayashi, Akihiro Yamamoto, Toshiya Hagihara, Yoshihiko Ito |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
organic chemicals
Acetylacetone Organic Chemistry food and beverages chemistry.chemical_element Alkylation Biochemistry chemistry.chemical_compound Tsuji–Trost reaction chemistry Nucleophile Drug Discovery Functional group Polymer chemistry Nucleophilic substitution Side chain Organic chemistry Palladium |
| Zdroj: | Tetrahedron Letters. 27:191-194 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/s0040-4039(00)83974-x |
| Popis: | Optically active ferrocenylphosphines containing a functional group on the side chain were effective as ligands for the palladium—catalyzed asymmetric allylic alkylation of 1,3-disubstituted allyl acetates such as l,3-diphenyl-3-acetoxy-l-propene with sodium acetylacetonate and related soft carbon nucleophiles to give the alkylation products of up to 92% ee. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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