Sesquiterpenoids from culture of the fungus Stereum complicatum (Steraceae): structural diversity, antifungal and phytotoxic activities
| Autor: | David E. Wedge, Wilmer H. Perera, Kumudini M. Meepagala, Stephen O. Duke |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Lemna
biology Agrostis stolonifera 010405 organic chemistry Chemistry Lactuca Plant Science Fungus biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences Stereum complicatum Stolonifera 010404 medicinal & biomolecular chemistry Botany Phytotoxicity Agronomy and Crop Science IC50 Biotechnology |
| Zdroj: | Phytochemistry Letters. 37:51-58 |
| ISSN: | 1874-3900 |
| DOI: | 10.1016/j.phytol.2020.03.012 |
| Popis: | Herein, we describe the isolation and identification of four new and three known sesquiterpenes from the culture broth of the fungus Stereum complicatum. Chemical structures were elucidated based on HR-DART-MS, 1D and 2D NMR experiments. Compounds were identified as sterostrein X (1), sterostrein Y (2), hirsutenol G (3), sterpurol C (4), sterostrein H (5), sterostrein P (6) and sterostrein Q (7). The phytotoxicity of 1-7 was assayed against Lactuca sativa, Agrostis stolonifera and Lemna paucicostata. Compounds showed slight or no activity against L. sativa, whereas 5 and 6 were the most active against A. stolonifera. Moreover, 5 was the only compound that was phytotoxic to L. paucicostata (IC50 46.2 μM). Compounds 2 and 5 slightly inhibited growth of B. cinerea and C. fragariae at 100 mM and C. acutatum at 50 mM, while 5 inhibited C. acutatum at 20 mM. Compound 6 was slightly active against all fungi at 20 mM. |
| Databáze: | OpenAIRE |
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