Total synthesis of the pyranocoumaronochromone lupinalbin H

Autor:	Mamoalosi A. Selepe, Siegfried E. Drewes, Fanie R. van Heerden
Rok vydání:	2011
Předmět:	Isoflavonoid Chemistry Organic Chemistry Drug Discovery Condensation Total synthesis Organic chemistry Moiety Ring (chemistry) Biochemistry Medicinal chemistry
Zdroj:	Tetrahedron. 67:8654-8658
ISSN:	0040-4020
DOI:	10.1016/j.tet.2011.09.042
Popis:	The pyranocoumaronochromone lupinalbin H was synthesized in three major steps, which involved preparation of 2′-hydroxygenistein by the Suzuki–Miyaura reaction, followed by oxidative cyclodehydrogenation into lupinalbin A. The final step was the regiospecific introduction of the dimethylpyran moiety to ring A of lupinalbin A via an aldol-type condensation with 3-methyl-2-butenal and 6π-electrocyclization.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1ae5ba20ab7871b6a1fcf45a5c8508fc https://doi.org/10.1016/j.tet.2011.09.042 Zobrazit plný text záznamu Full Text from ScienceDirect