Autor: |
F. Panicucci, P. M. Mannucci, S. Chiara, Janine Seger, J. Y. Muller, J. P. Allain, Zaverio M. Ruggeri, U. Baicchi, F. Mercuriali, D. Frommel |
Rok vydání: |
2009 |
Předmět: |
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Zdroj: |
Scandinavian Journal of Haematology. 23:64-68 |
ISSN: |
0036-553X |
DOI: |
10.1111/j.1600-0609.1979.tb02856.x |
Popis: |
The immunologic consequences of replacement therapy have been studied in 2 pairs of young haemophilic monozygotic twins. In both pairs one cotwin only developed a factor VIII specific antibody. This non-concordance illustrates the influence upon a specific immune response of non-genetic factors since the blood products, administered to each brother-pair, were not at all time identical nor were the regimens of transfusion therapy. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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