S1132 MELD Score as a Predictor of Mortality in Patients With SARS-CoV-2: A New Application for a Classic Scoring System
| Autor: | B. Al Abbasi, Nakeya Dewaswala, Karolina N. Dziadkowiec, Ahmed Abdallah, Jesus Pino, K. Gupta, Laura Suzanne K. Suarez, Samar Aboulenain, K. De Almeida, Fergie Ramos, Larnelle N. Simms, Peter Stawinski |
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| Rok vydání: | 2020 |
| Předmět: |
Creatinine
medicine.medical_specialty Hepatology business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Mortality rate Gastroenterology Retrospective cohort study Disease Single Center medicine.disease body regions chemistry.chemical_compound Liver disease chemistry Internal medicine Cohort medicine business |
| Zdroj: | American Journal of Gastroenterology. 115:S568-S569 |
| ISSN: | 1572-0241 0002-9270 |
| DOI: | 10.14309/01.ajg.0000706576.58856.d3 |
| Popis: | INTRODUCTION: The model for end-stage liver disease (MELD) score predicts liver disease severity based on serum creatinine, serum total bilirubin, and INR and has been shown to be useful in predicting mortality in patients with liver disease In late 2019, a novel coronavirus (SARS-CoV-2) was noted to cause an influenza-like disease with significant morbidity and mortality METHODS: This is a single center retrospective cohort study of patients diagnosed with 2019 Novel Coronavirus (SARS-CoV-2) between March of 2020 and May of 2020 Our study aimed to validate the utility of the MELD score in predicting mortality in patients diagnosed with SARS-CoV-2 The primary outcome is all cause in-hospital mortality The secondary outcomes include hospital lengthof- stay, ICU admission rate and ICU length of stay RESULTS: The MELD score was evaluated in a cohort of 71 patients The analysis included 31/71 (43 66%) men with a mean age of 66±16 years The median MELD score was 28 8 A cutoff value of 30 was assigned to stratify patients into low and high risk groups Mortality rate for patients with a MELD score (, 30) was 20 45% versus 45% (P = 0 0429 Hospital length of stay for patients with a low score was 6 13 days versus 7 7 days (P = 0 4560) ICU admission was 22 73% for patients stratified into the low group versus 45% (P = 0 0707) ICU length of stay for patients with a low score was 9 27 days versus 12 18 days (P = 0 4418) CONCLUSION: The MELD score is a valid prognostic score that can be used as a reliable predictor of mortality in patients with PCR-confirmed SARS-CoV-2 |
| Databáze: | OpenAIRE |
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