ChemInform Abstract: New Synthetic Route to Granulatimide and Its Structural Analogues

Autor:	Masayuki Murase, Masakazu Nishiyachi, Nobuyuki Nakashima, Eiichi Kotani, Takuji Yoshida
Rok vydání:	2010
Předmět:	Coupling (electronics) Granulatimide Chemistry Stereochemistry Product (mathematics) Didemnum granulatum General Medicine Stille reaction
Zdroj:	ChemInform. 33
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200248203
Popis:	The Stille coupling reaction of stannylindole 12 with 4-iodoimidazole 13 (or 24) in the presence of PdCl2(PPh3)2 gave the corresponding indole–imidazole coupling product 14 (or 25), thereby affording a new synthetic approach to the alkaloid granulatimide (7), isolated from the Brazilian ascidian Didemnum granulatum, as well as its structural analogues, 10-methylgranulatimide (23), 17-methylgranulatimide (30), 10,17-dimethylgranulatimide (31).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1aae71761a1012816197f73f5f5c509c https://doi.org/10.1002/chin.200248203 Zobrazit plný text záznamu Plný text