Autor: |
Michael D. Norenberg, Halima Gamrani, Amira Zaky, Arumugam R. Jayakumar, Lahoucine Bahi, Hicham Chatoui, Faical Isbaine, Lhoussaine Ammouta, Moulay Abdelmonaim El Hidan, Nadia Zouhairi, Tiziano Balzano, Omar El Hiba |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19 |
DOI: |
10.4018/978-1-7998-8225-1.ch007 |
Popis: |
Since December 2019, the world has been shaken by the spread of a highly pathogen virus, causing severe acute respiratory syndrome (SARS-Cov2), which emerged in Wuhan, China. SARS-Cov2 is known to cause acute pneumonia: the cardinal feature of coronavirus disease 2019 (COVID-19). Clinical features of the disease include respiratory distress, loss of spontaneous breathing, and sometimes neurologic signs such as headache and nausea and anosmia, leading to suppose a possible involvement of the nervous system as a potential target of SARS-CoV2. The chapter will shed light on the recent clinical and experimental data sustaining the involvement of the nervous system in the pathophysiology of COVID-19, based on several case reports and experimental data reporting the possible transmission of SARS-CoV2 throughout the peripheral nerves to the brain cardiorespiratory centers. Thus, understanding the role of the nervous system in the course of clinical symptoms of COVID-19 is important in determining the appropriate therapeutic approach to combat the disease. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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