Effect of Ethanol Leaf Extract of Moringa oleifera on Oxidative Stress and Atherogenic Indices of Otapiapia-Exposed Albino Rats
| Autor: | Love Nma Alison, C. U. Igwe, C. I. Iheme, Emeka E. Ezeokeke, L. A. Nwaogu |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Ethanol biology medicine.diagnostic_test 04 agricultural and veterinary sciences Malondialdehyde medicine.disease_cause Superoxide dismutase Toxicology Moringa 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology chemistry Distilled water Catalase 040102 fisheries biology.protein medicine 0401 agriculture forestry and fisheries Food science Lipid profile Oxidative stress |
| Zdroj: | Journal of Clinical Toxicology. |
| ISSN: | 2161-0495 |
| DOI: | 10.4172/2161-0495.1000350 |
| Popis: | Objective: Otapiapia is a locally produced, easily accessible, non-regulated household pesticide, which could easily contaminate human food. The ameliorative effect of ethanol leaf extract of Moringa oliefera on otapiapiainduced changes in oxidative stress, lipid profile and atherogenic indices of albino rats was investigated using standard methods. Methodology: Twenty-four apparently healthy Wister male albino rats (150-180 g) were divided into 4 groups (IIV) of 6 animals each. Group I served as the control, while group II animals were given otapiapia contaminated feed and distilled water. Group III were fed uncontaminated diet and M. oleifera extract drink. Group IV animals were also given the contaminated diet and M. oliefera extract. The feed and drinks were provided ad libitum for a period of 14 days. Result: The results show that intake of otapiapia significantly (p |
| Databáze: | OpenAIRE |
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