Enantioselective synthesis of 1-substituted tetrahydro-β-carboline derivatives via the asymmetric transfer hydrogenation
| Autor: | Piotr Roszkowski, Jan K. Maurin, Krystyna Wojtasiewicz, Tadeusz Lis, Andrzej Leniewski, Zbigniew Czarnocki |
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| Rok vydání: | 2005 |
| Předmět: |
Chemistry
Stereochemistry Process Chemistry and Technology Enantioselective synthesis chemistry.chemical_element Noyori asymmetric hydrogenation Transfer hydrogenation Catalysis Ruthenium chemistry.chemical_compound Amide Physical and Theoretical Chemistry Enantiomer Enantiomeric excess Chirality (chemistry) |
| Zdroj: | Journal of Molecular Catalysis A: Chemical. 232:143-149 |
| ISSN: | 1381-1169 |
| Popis: | Several 1-substituted-3,4-dihydro-β-carboline derivatives were subjected to asymmetric transfer hydrogenation catalysed by chiral ruthenium complexes to give both enantiomers of 1,2,3,4-tetrahydro-β-carbolines of high optical purity and in good yields. The absolute stereochemistry of 4c was established on the basis of X-ray analysis of its Mosher amide. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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