Preclinical Evaluation of the Effect of Antioxidant N­-acetyl-D-Glucosamine on Haematinic Potentials of Lauha Bhasm and Mandura Bhasm

Autor:	Wankhede S. B, Tenpe C. R, Lote S. B, Khobragade D. S, Potbhare M. S, Pardeshi K. S
Rok vydání:	2021
Předmět:	Pharmacology N Acetyl D Glucosamine Antioxidant Chemistry medicine.medical_treatment medicine
Zdroj:	Biomedical and Pharmacology Journal. 14:163-173
ISSN:	2456-2610 0974-6242
DOI:	10.13005/bpj/2111
Popis:	The effect of antioxidant N-acetyl-D-Glucosamine on haematinic activity of two ayurvedic haematinic preparations Lauha bhasm and mandura bhasm was studied in albino rats. Anaemia was induced by administration of phenyl hydrazine (80 mg/kg for 24 hrs) by intra-peritoneal injection. Changes in body weight, red blood cell count (RBC), white blood cell count (WBC), haemoglobin (HB) concentration and haematocrit (HCT) were analysed as indices of anaemia. The mean cell haemoglobin (MCH), mean cell volume (MCV) and mean cell haemoglobin concentration (MCHC) which are indicators of macrocytosis were calculated accordingly. Phenyl hydrazine induced a significant decrease (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1a80f48c223c5a5dca193909ced74374 https://doi.org/10.13005/bpj/2111 Zobrazit plný text záznamu