Open microfluidic gel electrophoresis: Rapid and low cost separation and analysis of DNA at the nanoliter scale
| Autor: | Roland Zengerle, Peter Koltay, Laurent Tanguy, L. Riegger, Ludwig Gutzweiler, Tobias Gleichmann |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Gel electrophoresis chemistry.chemical_classification Materials science Fabrication Capillary action Clinical Biochemistry Microfluidics Evaporation Nanotechnology 02 engineering and technology Polymer 021001 nanoscience & nanotechnology Chip Biochemistry Analytical Chemistry 03 medical and health sciences Electrophoresis 030104 developmental biology chemistry 0210 nano-technology |
| Zdroj: | ELECTROPHORESIS. 38:1764-1770 |
| ISSN: | 0173-0835 |
| DOI: | 10.1002/elps.201700001 |
| Popis: | Gel electrophoresis is one of the most applied and standardized tools for separation and analysis of macromolecules and their fragments in academic research and in industry. In this work we present a novel approach for conducting on-demand electrophoretic separations of DNA molecules in open microfluidic (OM) systems on planar polymer substrates. The approach combines advantages of slab gel, capillary- & chip-based methods offering low consumable costs ( |
| Databáze: | OpenAIRE |
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