Production of an antibody-like factor in the sea star Asterias rubens: Role of the gastric haemal tufts

Autor: C. Brillouet, Michel Leclerc
Rok vydání: 1986
Předmět:
Zdroj: Cell Biology International Reports. 10:307-313
ISSN: 0309-1651
DOI: 10.1016/0309-1651(86)90001-9
Popis: Cells from the axial organ (AO) of sea stars stimulated “in vivo” with TNP coupled to polyacrylamide beads and subsequently cultured “in vitro” were able to produce an antibody-like factor which induced the lysis of mammalian red cells sensitized with TNP. Three types of cells at least are involved in the production of the antibody-like factor. The addition of 2-mercapto-ethanol to the cultures including these 3 populations was essential but what is a novelty is the fact that cells from the gastric haemal tufts (G.H.T.), probably phagocytes, are able to replace it. Otherwise G.H.T. contain cells playing the role of nylon wool- non adherent AO cells or T like cells.
Databáze: OpenAIRE