Maternal predictors of early breast milk output
| Autor: | RJ Greenwood, L McGrath, M. W. Woolridge, Jenny Ingram |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
education.field_of_study business.industry medicine.drug_class Population Gestational age Physiology General Medicine Breast milk Prolactin medicine.anatomical_structure Endocrinology Thyroid-stimulating hormone Estrogen Internal medicine Lactation Pediatrics Perinatology and Child Health medicine business education Breast feeding |
| Zdroj: | Acta Paediatrica. 88:493-499 |
| ISSN: | 0803-5253 |
| DOI: | 10.1111/j.1651-2227.1999.tb00164.x |
| Popis: | Previous attempts to show a quantitative relationship between maternal hormone levels and early milk output have used small sample sizes and simple correlations. Women of mixed parity and similar socio-economic status and education were recruited to a study using multivariate analysis to look for these associations. Hormone levels (oestradiol, progesterone, prolactin and thyrotropin (TSH)) were determined for 91 mothers at four time points (ante- and postnatally) from finger-prick blood spots by fluoro-immunoassay. Milk output at 1 and 4 weeks was determined from 24-h test weighings. Parity was found to be the most significant factor affecting breast milk volume at 1 wk postpartum (multiparous women delivered 142 ml more milk in 24 h than primiparous women). Total time spent feeding had a strong association with breast milk volume, with increasing time having a negative effect. Multiple regression analysis, controlling for parity and time spent feeding, showed a positive association of milk output at 1 wk with antenatal progesterone and antenatal prolactin levels. At 4 wk, higher postpartum oestradiol levels had a negative association and antenatal progesterone levels a positive association with milk output. This study demonstrates that there are quantitative associations between antenatal maternal hormone levels and breast milk output in the early postnatal period. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text