Estrogen receptors in male breast cancer: Clinical and pathologic correlations

Autor:	Emmanuel M. Dandolos, Michael A. Friedman, Michael D. Lagios, William H. Johnston, Philip G. Hoffman, Pentii K. Siiteri
Rok vydání:	1981
Předmět:	Oncology Cancer Research medicine.medical_specialty business.industry Incidence (epidemiology) Estrogen receptor medicine.disease Breast cancer Male patient Male breast cancer Internal medicine Medicine Hormonal therapy business
Zdroj:	Cancer. 47:134-137
ISSN:	1097-0142 0008-543X
DOI:	10.1002/1097-0142(19810101)47:1<134::aid-cncr2820470122>3.0.co;2-m
Popis:	Breast cancer tissue from 12 male patients was evaluated for the presence of estrogen receptors (ER), and at least 10 of 12 were found to be high in ER (ER +). A combination of previously published cases and our own experience indicates that 80% of patients (37/47) have ER+ tumors. This incidence of ER positivity in men is greater than that in women with breast cancer. Clinical responses to hormonal therapy have been observed in the ER+ patients but not in one ER– patient. Measurement of ER may be clinically important in men with breast cancer.
Databáze:	OpenAIRE
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