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Publisher Summary Many prospective chemist employees are recruited to become industrial medicinal chemists with scant prior exposure to the field itself or to biology. When it comes to hiring such chemists, the pharmaceutical employer generally seeks out the brightest and most dynamic synthetic organic chemists most often with a Ph.D. and postdoctoral experience in the laboratory of well known and well-regarded professors of organic chemistry. The newly appointed chemists have to discover rapidly how to synthesize new molecules suitable for focused biological testing. A fully rewarding intellectual experience requires an appreciation of the reasons for making the compounds. They must learn to interface with diverse biological scientists, for example, to converse knowingly with biochemists, pharmacologists, toxicologists, molecular biologists, and formulation scientists to be actively involved in the drug design. The question arises whether such chemists have had adequate university training and whether they should have received much more exposure to medicinal chemistry concepts while at university. This issue of the optimal educational experience for medicinal chemists has been a matter for discussion by the medicinal chemistry section of The International Union of Pure and Applied Chemistry. A working party has been set up to consider a medicinal chemistry curriculum that addressed these issues. It was decided to seek the viewpoint, from an industrial perspective, of what academic training (if any) should be provided in medicinal chemistry and a questionnaire was devised. This chapter includes detail discussion of this questionnaire. |
