Glycosyltransferase Levels in Tumors Metastatic to Liver and in Uninvolved Liver Tissue 2

Autor:	Elizabeth Sykes, Michael D. Henderson, David Kessel
Rok vydání:	1977
Předmět:	chemistry.chemical_classification Galactosyltransferase Cancer Research Fucosyltransferase biology Sialyltransferase Cancer medicine.disease Enzyme Oncology chemistry Liver tissue Glycosyltransferase Immunology Galactosyltransferase activity biology.protein medicine Cancer research
Zdroj:	JNCI: Journal of the National Cancer Institute. 59:29-32
ISSN:	1460-2105 0027-8874
DOI:	10.1093/jnci/59.1.29
Popis:	Elevated levels of three plasma glycosyltransferases were associated with neoplasia in cancer patients, notably those with tumor metastatic to liver. We examined levels of sialyltransferase, galactosyltransferase, and fucosyltransferase in metastatic tumor and apparently uninvolved host liver tissue in attempts to delineate possible sources of elevated plasma enzyme levels. Highest levels of fucosyltransferase activity were found associated with tumor tissue; in contrast, sialyltransferase and galactosyltransferase activity was often highest at the tumor-liver interface.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1a475b2f2abc08786c719ff01a17f33d https://doi.org/10.1093/jnci/59.1.29 Zobrazit plný text záznamu