ChemInform Abstract: Toward Preparative Resolution of Chiral Alcohols by an Organic Chemical Method

Autor:	Valerie Sage, Euneace Teoh, Cornelis Matthijs Moorhoff, Dilek Saylik, Christopher R. Strauss, Nino Malic, Janet L. Scott
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Resolution (mass spectrometry) Chemistry Diastereomer Organic chemistry Alcohol General Medicine Enantiomer Tertiary alcohols Catalysis
Zdroj:	ChemInform. 41
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.201030025
Popis:	Asymmetric alcohols were resolved as 1-α-O-alkyl-2,3-unsaturated hexosides. After separation of diastereoisomers, the auxiliary and the enantiomeric alcohol were recovered by transglycosidation. Potential applications include resolution of labile secondary and tertiary alcohols, difficult by existing techniques, and enhancement of ees of chiral alcohols produced enzymatically or by synthetic catalytic methods.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1a44b1cbef5329b70c3e0577bdc296f0 https://doi.org/10.1002/chin.201030025 Zobrazit plný text záznamu Plný text