| Autor: |
Ingmar Königsrainer, Alfred Königsrainer, Philipp Horvath |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Peritoneal Tumors and Metastases ISBN: 9783030626396 |
| DOI: |
10.1007/978-3-030-62640-2_10 |
| Popis: |
The peritoneal metastasis of primary gastrointestinal and gynecological tumors requires not only the resection of the primary tumor but also the removal of the involved parietal and visceral peritoneum. The complete macroscopic removal of all tumor foci represents the basis of the peritonectomy procedure in terms of a curative treatment. The microscopic tumor cells remaining after a complete cytoreduction are treated by an application of an intraoperative hyperthermic chemotherapy. Extensive peritonectomy procedures without subsequent HIPEC (hyperthermic intraperitoneal chemotherapy) treatment can raise the recurrence rates along the peritoneal dissection areas. The underlying pathophysiological mechanisms were summarized by P.H. Sugarbaker in his “Tumor Cell Entrapment Hypothesis” (Sugarbaker et al. Cytoreductive surgery & perioperative chemotherapy for peritoneal surface malignancy: textbook and video atlas. Woodbury: Cine-Med; 2013). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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