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Background: Advances in Percutaneous Coronary Inter-vention (PCI) techniques have improved patient outcome. However, occurrence of myonecrosis after elective PCI has been extensively debated.Aim of Study: We investigated the value of the ratio of early transmittal velocity to tissue Doppler mitral annular early diastolic velocity (E/E') in detecting the occurrence of peri-procedural myocardial injury in patients undergoing elective PCI.Patients and Methods: Sixty two patients undergoing elective PCI were recruited prospectively. All participants had EF% >50% and sinus rhythm. E/E' ratio was measured immediately before, and within 24 hours after PCI. CK-MB and cardiac troponin (cTn) were measured in the same day after successful PCI to diagnose myocardial injury.Results: The cohort age was 56.7±9.7 year, and consisted of forty four (71%) males, 49 (27.4%) had ³ two risk factors for CAD, 60% were symptomatic before PCI. Thirty (48.4%) patients had regional wall motion abnormalities (regional Wall Motion Score Index (WMSI): 0.74±0.29). Myocardial injury was diagnosed by elevated cTn in 39 (62.9%) patients. Patients with predilation showed reduction of LVEDP as estimated by D E/E' (8.9±2.9 Vs. 7.9±3.2, p |
