Matrix metalloproteinase expression and localization in turkey (Meleagris gallopavo) during the endochondral ossification process1
| Autor: | S. Simsa, E. Monsonego Ornan, O. Genina |
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| Rok vydání: | 2007 |
| Předmět: |
Data source
medicine.medical_specialty Ossification General Medicine Matrix metalloproteinase Biology biology.organism_classification Embryonic stem cell Cell biology Extracellular matrix Endocrinology Internal medicine Genetics medicine Animal Science and Zoology medicine.symptom Endochondral ossification Meleagris gallopavo Food Science |
| Zdroj: | Journal of Animal Science. 85:1393-1401 |
| ISSN: | 1525-3163 0021-8812 |
| DOI: | 10.2527/jas.2006-711 |
| Popis: | Vertebrate long bones are formed by endochondral ossification, a process accompanied by changes in extracellular matrix synthesis and remodeling, performed mainly by the matrix metalloproteinases (MMP). The temporal/spatial expression patterns of 5 members of the MMP family known to be important for endochondral ossification were studied, for the first time, in the turkey growth plate during embryonic and juvenile stages. The expression of MMP-2 was detected in the proliferative zone, MMP-3, MMP-9, and MMP-13 in cells lining the blood vessels; MMP-13 was also detected in hypertrophic chondrocytes. The MMP-16 expression was detected in the reserve zone of the growth plate. These results present a detailed survey of turkey MMP, serving as a data source (atlas) for further studies in this subject. |
| Databáze: | OpenAIRE |
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