Abstract 553: High-Intensity Interval Training Partly Restores Thrombotic Microangiopathy in an Experimental Model of Hypertensive Renal Injury
| Autor: | Gustavo J Silva, Knut A Langlo, Natale Rolim, Jose B Moreira, Alessandra Medeiros, Marcia Alves, Xiaojuan Yang, Till Gusky, Paulina Lesko, Fredrik H Bækkerud, Henning O Ness, Knut Aasarød, Stein I Hallan, Ulrik Wisløff |
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| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Hypertension. 64 |
| ISSN: | 1524-4563 0194-911X |
| Popis: | To investigate whether high intensity interval training can reduce hypertensive renal injury in Dahl salt-sensitive rats. Adult females Dahl salt-sensitivity (Dahl SS) rats were randomized in three groups: sedentary low-salt diet (LS, N=20: 0.3% NaCl), sedentary high-salt diet (HS, N=40: 8% NaCl) or high-salt diet submitted to high intensity interval training (HIT, N=20: 8% NaCl + HIT, 3x38 min/wk; 60% HRmax adding 4 intervals of 4 min at 90% HRmax). After 30 weeks of follow-up, 24h urine has been collected in metabolic cages, followed by tissue harvesting. HIT did not affect the development of hypertension induced by high-salt intake in the Dahl SS rats (147±55 vs 209±80* vs 203±79* mm Hg, for LS, HS and HIT, respectively; *p |
| Databáze: | OpenAIRE |
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