Profile of cord blood lipids in term newborns in parakou (Benin)
| Autor: | Simon Akpona, Moutawakilou Gomina, Gloria Amevor, Achille Obossou, Tarik Salifou |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Cord medicine.diagnostic_test Triglyceride Cholesterol Obstetrics Blood lipids Umbilical cord 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine.anatomical_structure chemistry Hypotriglyceridemia 030225 pediatrics Cord blood medicine lipids (amino acids peptides and proteins) 030212 general & internal medicine Lipid profile |
| Zdroj: | International Journal of Clinical Biochemistry and Research. 7:111-115 |
| ISSN: | 2394-6377 2394-6369 |
| Popis: | Introduction: Lipid profile abnormalities at birth indicate that initial genetic inheritance is already at risk of developing a cardiovascular disease. Objective: Investigate the profile of umbilical cord blood lipids of term newborns in Parakou (Benin). Materials and Methods: This research work was a cross-sectional study with descriptive and analytical purpose, based on prospective collection of data. It involved term newborns recruited through complete census in three health-care facilities located in the city of Parakou (Republic of Benin), after the informed consent read and approved by their respective mothers and ethics advice. The study data were collected from March 1 to May 30, 2017 by measurements of anthropometric and lipid parameters from umbilical cord blood using endpoint enzymatic methods. LDL cholesterol was obtained by Friedewald formula. Results: A total of 120 newborns were recruited (60 males and 60 females). Their mean weight was estimated at 2992.68 355.08 g with extremes from 2120 to 3125 g. The mean values of lipid parameters were: total cholesterol (0.68 0.25 g/L), HDL cholesterol (0.29 0.12 g/L), LDL cholesterol (0.31 0.16 g/L) and triglyceride (0.39 0.27 g/L). There was no significant difference in mean values of newborns ’ lipid parameters between both sexes (p > 0.05). Total cholesterol and HDL cholesterol were normal, respectively in 75.83% and 85% of cases; hypotriglyceridemia was observed in 61.67% of newborns. Keywords: Newborn, Lipids, Hypotriglyceridemia, Umbilical cord, Benin. |
| Databáze: | OpenAIRE |
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