| Popis: |
Background: Patients with Chronic Obstructive Pulmonary Disease (COPD) and Heart Failure (HF) have higher prevalence of Endothelial Dysfunction (ED), which leads to a worse prognosis. It has been observed that several nutrients or eating patterns, such as the Mediterranean diet, improves clinical indicators and prognosis. However, there is lack of evidence about the impact of the nutrients on the endothelium in patients with COPD and HF. Purpose: To determine the association between ED and nutrient consumption in subjects with COPD and HF. Methods: A cross-sectional study enrolled 199 subjects with diagnosis of COPD and HF. Subjects with asthma and cancer were excluded. The ED was assessed by photoplethysmography. The nutrient consumption was evaluated by the 24-hour reminder and analyzed with the FoodProcesor® program. Results: The mean age was 70.50 ± 11.70, 56.8% were women, 65.9% had cachexia. The subjects with ED were older (71.11 ± 11.32 vs 66.70 ± 13.42, p = 0.068), as well as, lower calorie consumption (1445.30 ± 596.39 vs 1688.43 ± 598.94, p = 0.051) compared to subjects without ED. No difference was observed in weight, height and comorbidities. When evaluating the effect of nutrients on the risk of presenting ED we found that calcium intake [OR: 0.99, IC 95%: 0.99 – 0.99, p = 0.026], phosphorus [OR: 0.99, IC 95% 0.99 – 0.99, p = 0.030], copper [OR: 0.40, IC 95%: 0.15 – 1.04, p = 0.062] and insoluble fiber [OR: 0.92, IC 95%: 0.85 – 0.99, p = 0.036] reduces the risk of ED. No association was observed in the rest of the nutrients. Conclusion: An adequate intake of calcium, phosphorus and insoluble fiber reduces the risk of ED. |
