Gastro retentive drug delivery systems: An overview
| Autor: | Neeta, Saurabh Satija, Meenu Mehta, Sanchit Mahajan, Parijat Pandey |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Superporous hydrogels digestive oral and skin physiology High density Gastric emptying time Biology Gastro retentive Dosage form Drug delivery medicine Pharmacology (medical) Pharmaceutical sciences Intensive care medicine Patient compliance Pharmacology Toxicology and Pharmaceutics (miscellaneous) |
| Zdroj: | Research Journal of Pharmacy and Technology. 11:2157 |
| ISSN: | 0974-360X 0974-3618 |
| DOI: | 10.5958/0974-360x.2018.00398.0 |
| Popis: | Orally administered gastro retentive dosage forms draws great attention in the pharmaceutical research industry. These systems improved patient compliance with increased therapeutic index of drugs increase importance of gastro-retentive drug delivery systems (GRDDS). Numerous physiological constraints associated with gastroretentive dosage forms such as short gastric retentive time, variations in gastric emptying time can be reduced by various technological advanced utilized in the design and fabrication of gastroretentive dosage. Currently different development approaches are utilized to increase gastric retention time, including High density systems, Expanding systems, Unfoldable and Swellable systems and Superporous hydrogels. The present review briefly addresses various gastroretentive dosage forms for prolongation gastric residence time. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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