Biofabrication of controllable alginate hydrogel cell scaffolds based on bipolar electrochemistry

Autor: Fei Xie, Changyue Li, Xiaoqing Hua, Li Ma
Rok vydání: 2021
Předmět:
Zdroj: Journal of Bioactive and Compatible Polymers. 36:497-509
ISSN: 1530-8030
0883-9115
DOI: 10.1177/08839115211053920
Popis: Bipolar electrochemistry successfully realized the electrodeposition of calcium alginate hydrogels in specific target areas in tissue engineering. However, the shape and quantity of three-dimensional cannot be accurately controlled. We presented a novel growth model for fabricating hydrogels based on bipolar electrochemical by patterned bipolar electrodes using photolithography. This work highlights pattern customization and quantitative control of hydrogels in cell culture platforms. Furthermore, alginate hydrogels with different heights can be controlled by adjusting the key parameters of the growth model. This strategy exhibits promising potential for cell-oriented scaffolds in tissue engineering.
Databáze: OpenAIRE