Interactions Of Liposomes And Ige. Immunoassay And Fluorescence Study

Autor:	Zygmunt H. Zawada
Rok vydání:	1999
Předmět:	Hydrophobic effect Liposome Blue dextran medicine.diagnostic_test biology Chemistry Sodium channel Immunoassay medicine biology.protein Biophysics Immunoglobulin E Fluorescence
Zdroj:	Spectroscopy of Biological Molecules: New Directions ISBN: 9789401059190
DOI:	10.1007/978-94-011-4479-7_174
Popis:	Liposomes are removed from circulation by normal methabolism of phospholipids on one hand, and on the other — as cell-similar structures are the subject of the immunological response especially when they are carriers of protein or petyde anti-genes [1]. Encapsulation of proteins or peptydes must be correlated with their partial exhposition on the external surface of a liposome [2]. Additionally, some domains of the immunoglobulines show significant similarity of sequences to the voltage-gated sodium channels [3]. This suggests that hydrophobic interaction of immuboglobines with the liposomes surface. The aim of the work was to study non-covalent bonds of the immonoglobulin E with the liposome surface and to evaluate the immunological activity of the surface-bound IgE.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::191003a51e97b5c0c1ba2fd63595ae6e https://doi.org/10.1007/978-94-011-4479-7_174 Zobrazit plný text záznamu