CHARACTERISTIC OF ANEMIC SYNDROME IN ONCOLOGIC PATIENTS WITH SEPSIS IN THE EARLY POST-OPERATIVE PERIOD
| Autor: | Valentina Nikolaevna Blindar, G N Zubrikhina, A V Sytov, M. M. Dobrovolskaya, T. V. Davydova, N. A. Pluzhnikova |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry Microcytosis Biochemistry (medical) Cancer General Medicine Iron deficiency 030204 cardiovascular system & hematology medicine.disease Gastroenterology Sepsis 03 medical and health sciences Medical Laboratory Technology 0302 clinical medicine Erythropoietin 030220 oncology & carcinogenesis Internal medicine Hypochromia medicine Erythropoiesis business Normal range medicine.drug |
| Zdroj: | Russian Clinical Laboratory Diagnostics. 65:169-173 |
| ISSN: | 0869-2084 |
| Popis: | A study of the main indicators of red blood (RBC, HGB, HCT, MCV, MCH) and the concentration of EPO, sTfR in 9 cancer patients with anemic syndrome (AS) against sepsis was carried out. Among them, patients with chronic disease anemia (ACh), with normocytic, normochromic characteristics of red blood cells and low hematocrit predominated. In 2 patients, microcytosis and erythrocyte hypochromia were noted, the concentration of sTfR was significantly higher than normal (0.9 ± 0.07 μg / ml), amounted to 2.7 μg / ml in one of them and 1.9 μg / ml in the other, which testified to t iron deficiency erythropoiesis (IDE) on the background of the ACh,. In 7 patients with ACh without IDE, sTfR values were within the normal range (0.1-1.2) μg / ml, the median was 0.5 μg/ml. In all patients with sepsis, the production of EPO was inadequate for the severity of the AS, to a lesser extent in patients with IDE. The average EPO production in the group was 19.4 ± 5.1 (7.7-52.8) mU / ml, median = 12.1 mE / ml. Further studies of EPO, sTfR are planned in order to determine their role in therapeutic tactics in the correction of AS in cancer patients with sepsis. |
| Databáze: | OpenAIRE |
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