Response of rats to hyperbaric oxygen after preliminary adaptation to hypoxia

Autor: Z. I. Barbashova, A. I. Selivra
Rok vydání: 1978
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 85:274-276
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00801333
Popis: Preliminary adaptation of rats to hypoxia under conditions increasing resistance to many stressproducing agents not only had no protective effect against exposure to hyperbaric oxygen at pressures up to 6 kgf/cm2 but, conversely, lowered the resistance of the animals. The latent period of onset of seizures in the adapted rats was shortened especially if exposure to hyperbaric oxygen began 1 or 2 days after the end of adaptation to hypoxia, and was a little shorter in the experiments carried out after 3–4 days. The responses returned completely to normal 1 month after the end of adaptation to hypoxia. The possible causes of development of the phenomena are discussed.
Databáze: OpenAIRE
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