Silica-bonded chiral stationary phases with structurally simple π-donor chiral selectors for high-performance liquid chromatography

Autor:	Laureano Oliveros, B. Desmazieres, Cristina Minguillon, P.L. Desbène
Rok vydání:	1992
Předmět:	Chiral column chromatography Chromatography Chemistry Organic Chemistry General Medicine Chiral stationary phase Chiral derivatizing agent Biochemistry High-performance liquid chromatography Analytical Chemistry
Zdroj:	Journal of Chromatography A. 589:53-59
ISSN:	0021-9673
DOI:	10.1016/0021-9673(92)80005-f
Popis:	Seven new chiral stationary phases obtained from ( S )-phenylalanine derivatives, ( R )-Mosher's acid and ( S )-naproxen were prepared and evaluated. The racemic substances used to test them contained either π-acidic or π-basic sites. The best results were observed when the chiral entity bonded to γ-aminopropylsilica gel was 3,5-dimethylanilido-, 3,5-dimethylbenzoyl- or 3,5-dimethoxybenzoyl-( S )-phenylalanine and -( S )-naproxen.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::18cf2dece19f758c6a254a23eac5b4ac https://doi.org/10.1016/0021-9673(92)80005-f Zobrazit plný text záznamu