| Popis: |
Mathematical models have been used to understand the factors that govern infectious disease progression in viral infections. In this paper, based on the standard mass action incidence, an anti-HBV therapy model with time-delayed immune response is set up. The time-delay is used to describe the period of time for antigenic stimulation to generate CTLs. The globally asymptotically stable analysis of the infection-free equilibrium is given in the paper. Some conditions for Hopf bifurcation around endemic equilibrium to occur are also obtained by using the time delay as a bifurcation parameter. |
