Suzuki-type cross-coupling reaction of 1-benzyl-2-iodo-1H-benzimidazoles with aryl boronic acids: A regioselective route to N-alkylated 6-alkoxy-2-aryl-1H-benzimidazoles

Autor:	José L. García-Navío, Juan J. Vaquero, Alfredo Pastor, Carlos Lamas, Jesús Ezquerra
Rok vydání:	1997
Předmět:	Aryl Organic Chemistry Regioselectivity chemistry.chemical_element Alkylation Biochemistry Medicinal chemistry Coupling reaction Catalysis chemistry.chemical_compound chemistry Drug Discovery Alkoxy group Organic chemistry Palladium
Zdroj:	Tetrahedron. 53:12755-12764
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(97)00795-3
Popis:	The Suzuki-type cross-coupling reaction of 6-substituted 1-benzyl-2-iodo-1H-benzimidazoles with aryl boronic acids provided an efficient synthesis of the corresponding 2-ary-1H-benzimidazoles. The reaction was catalyzed by palladium(0) under different conditions depending on the aryl group substitution.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::188ad86a50708447bbf19e66abbf1895 https://doi.org/10.1016/s0040-4020(97)00795-3 Zobrazit plný text záznamu Full Text from ScienceDirect