High-Throughput Cryo-EM Enabled by User-Free Preprocessing Routines

Autor: Li, Y, Cash, JN, Tesmer, JJG, Cianfrocco, MA
Rok vydání: 2020
Předmět:
DOI: 10.7302/7634
Popis: Li et al. develop an automatic preprocessing workflow for single-particle cryo-EM. This workflow produces high-resolution particle stacks from micrograph inputs without subjective decision making. They used this workflow to automatically preprocess and analyze six challenging datasets, demonstrating that the workflow correctly identified the high-resolution dataset amid five bad datasets.
Databáze: OpenAIRE