Perinatale Morbidität in Schwangerschaften von präkonzeptionellen Diabetikerinnen und Gestationsdiabetikerinnen im Vergleich mit Nichtdiabetikerinnen. Ergebnisse der Niedersächsischen Perinatalerhebung

Autor: H. H. Günter, Peter Hillemanns, P. Wenzlaff, Holger Maul, H. Hertel, A. Scharf
Rok vydání: 2006
Předmět:
Zdroj: Zeitschrift für Geburtshilfe und Neonatologie. 210:200-207
ISSN: 1439-1651
0948-2393
DOI: 10.1055/s-2006-957073
Popis: OBJECTIVE Pregnancies of women with glucose tolerance disorders are still associated with high maternal and perinatal morbidity. In the present population-based study, we investigated the fetal and neonatal risks and complications in pregnancies of women with preconceptional and gestational diabetes in comparison with pregnancies of non-diabetic women. METHODS A total of 913,255 pregnancies with 926,685 newborns documented by the Perinatal Registry of Lower Saxony, Germany, between 1987 and 1999 was retrospectively evaluated. In particular, the obstetric parameters of 3439 women with preconceptional diabetes mellitus (PDM, n = 3485 neonates), 4051 women with gestational diabetes mellitus (GDM, n = 4155 neonates) and 905,765 non-diabetic women (NDM, n = 919.053 neonates) were analysed. RESULTS The diabetes groups had a higher rate of preterm birth 4500 g (OR 2.775 and 2.742, respectively) and >95. percentile (OR 4.268 and 3.610, respectively) in newborns of diabetic women. The higher rate of umbilical arterial pH < 7.00 (OR 2.481 and 1.195, respectively) as well as Apgar score at 1 minute
Databáze: OpenAIRE